Expertenkommentare

Der Expertenbeirat der Stiftung LebensBlicke setzt sich aus ärztlichen Kolleginnen und Kollegen zusammen, die auf dem Gebiet der Darmkrebsvorsorge und -früherkennung sowie der – therapie besondere Expertise haben.

2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006



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2017


PPI und Mikrobiom des Darms – eine gefährliche Interaktion?
Imhann F et al. Proton pump inhibitors affect the gut microbiome. Gut 2016;65:740
Kommentar: Prof. Dr. Joachim Labenz, Siegen, 21.06.2017


Factors associated with colorectal cancer occurrence after colonoscopy that did not diagnose colorectal cancer
Cheung D. et al.; Gastrointestinal Endoscopy 2016; 84:287-295.
Kommentar: Prof. Dr. Siegbert Faiss, Hamburg, 26.05.2017


Narrow band imaging optical diagnosis of small colorectal polyps in routine clinical practice: the Detect Inspect Characterise Resect and Discard 2 (DISCARD 2) study
Rees CJ, Rajasekhar P, Wilson A, et al. Gut 2017;66:887-895.
Kommentar: Dr. med. Rainer Bastian, PD. Dr. med. Brigitte Schumacher, 20.05.2017


Fusobacterium nucleatum increases proliferation of colorectal cancer cells and tumor development in mice by activating toll-like receptor 4 signaling to nuclear factor-kappaB, and up-regulating expression of microRNA-21
Yang YS, Weng W, Peng J, Hong L et al., Gastroenterology 2017;152:851-866
Kommentar: PD Dr. Georgia Schilling, Hamburg, 04.05.2017


Clinical and Molecular Characteristics of Post-Colonoscopy Colorectal Cancer: A Population-based Study
Stoffel E, Erichsen R, Frøslev T, Pedersen L, Vyberg M, Koeppe E, Crockett SD, Hamilton SR, Sørensen HT, Baron JA
Kommentar: Prof. Dr. Hendrik Bläker, Berlin, 21.04.2017


Increased Risk of Colorectal Cancer Development Among Patients With Serrated Polyps
Rune Erichsen, John A. Baron, Stephen J. Hamilton-Dutoit, Dale C. Snover, Emina Emilia Torlakovic, Lars Pedersen, Trine Frøslev, Mogens Vyberg, Stanley R. Hamilton, and Henrik Toft Sørensen, Gastroenterology 2016;150:895–902
Kommentar: Prof. Dr. med. Thomas Frieling, Krefeld, 16.04.2017


Chemoprevention of colorectal cancer in individuals with previous colorectal neoplasia: systematic review and network meta-analysis
Dulai P. S. et al, BMJ, 2016, 355:i6188
Kommentar: Prof. Dr. Cornelia Ulrich und Caroline Himbert, Salt Lake City, 21.3.2017


Effectiveness of Screening Colonoscopy to Prevent Colorectal Cancer Among Medicare Beneficiaries Aged 70 to 79 Years
Garcia-Albéniz et al. Ann Intern Med 2017; 166:18-26
Kommentar: Prof. Dr. Christian Ell, Offenbach, 20.03.2017


Comparison of Targeted vs Random Biopsies for Surveillance of Ulcerative Colitis Associated Colorectal Cancer
Watanabe T, Ajioka Y, Mitsuyama K, Watanabe K, Hanai H, Nakase H, Kunisaki R, Matsuda K, Iwakiri R, Hida N, Tanaka S, Takeuchi Y, Ohtsuka K, Murakami K, Kobayashi K, Iwao Y, Nagahori M, Iizuka B, Hata K, Igarashi M, Hirata I, Kudo SE, Matsumoto T, Ueno F, Watanabe G, Ikegami M, Ito Y, Oba K, Inoue E, Tomotsugu N, Takebayashi T, Sugihara K, Suzuki Y, Watanabe M, Hibi T. Gastroenterology. 2016 Dec; 151(6):1122-1130.
Kommentar: Prof. Dr. med. Raja Atreya; Erlangen, 19.03.2017


Cost-Effectiveness of Alternative Colonoscopy Surveillance Strategies to Mitigate Metachronous Colorectal Cancer Incidence
Erenay FS, Alagoz O, Banerjee R, Said A, Cima RR. Cancer. 2016 Aug 15;122(16):2560-70
Kommentar: Dr. W. Rimili, Prof. Dr. K. Beckh, Worms, 13.03.2017


Post-Colonoscopy Complications: A Systematic Review, Time Trends, and Meta-Analysis of  Population-Based Studies
Ankie Reumkens ,  Eveline J.A. Rondagh , C. Minke Bakker, Bjorn Winkens , Ad A.M. Masclee, Silvia Sanduleanu. Am J Gastroenterol 2016; 111:1092–1101; doi: 10.1038/ ajg.2016.234; published online 14 June 2016
Kommentar: Prof. Dr. Jörg G. Albert, Stuttgart, 28.02.2017


Bariatric Surgery versus Intensive Medical Therapy for Diabetes – 5-Year Outcomes
Philipp R. Schauer, MD; Deepak L. MD, MPH Jon P. Kirwan, N Engl J Med 2017;376:641-51
Kommentar: Prof. Dr. Werner Hohenberger, Erlangen, 28.02.2017


Yield of a second screening colonoscopy 10 years after an initial negative examination in average-risk individuals
PL Ponugoti, DK Rex, Gastrointestinal Endoscopy 01/2017, 85: 221-224
Kommentar: Prof. Dr. Michael Jung, Mainz, 23.02.2017


Aspirin as secondary prevention in patients with colorectal cancer: an unselected population-based study
Bain S. J. et al, Journal of Clinical Oncology, 2016, 34:2501-2508
Kommentar: Prof. Dr. Cornelia Ulrich und Caroline Himbert, Salt Lake City, 30.1.2017


Association between Results of a Gene Expression Signature Assay and Recurrence-Free Interval in Patients With Stage II Colon Cancer in Cancer and Leukemia Group B 9581 (Alliance)
Donna Niedzwiecki, Wendy L. Frankel, Alan P. Venook, Xing Ye, Paula N. Friedman, Richard M. Goldberg,Robert J. Mayer, Thomas Anthony Colacchio, Jude Marie Mulligan, Timothy S. Davison, Eamonn O’Brien, Peter Kerr, Patrick G. Johnston, Richard D. Kennedy, D. Paul Harkin, Richard L. Schilsky, Monica M. Bertagnolli, Robert S. Warren, and Federico Innocenti. J Clin Oncol. 2016 Sep 1;34(25):3047-53
Kommentar: PD Dr. Alexander Hagel, Prof. Dr. Markus Neurath, Erlangen, 27.01.2017


Understanding the contribution of family history to colorectal cancer risk and its clinical implications: A state-of-the-science review
Lowery et al., Cancer 09/2016
Kommentar: PD Dr. Georgia Schilling, Hamburg, 10.01.2017


Prevalence, distribution and risk of sessile serrated adenomas/polyps at a center with a high adenoma detection rate and experienced pathologists
E.G. Joep et al.; Endoscopy 2016; 48: 740–746
Kommentar: Prof. Dr. med. Siegbert Faiss, Hamburg, 02.01.2017


Endoscopic mucosal resection: learning curve for large nonpolypoid colorectal neoplasia
Bhurwald A et al., Gastrointestinal Endoscopy 2016;84:959-968
Kommentar: PD Dr. med. Dirk Hartmann, Berlin, 01.01.2017

2016


Paradigm shift in the surveillance and management of dysplasia in IBD
Soetniko et al. Digestive Endoscopy 2016; 28: 266-273
Kommentar: Prof. Dr. Max Reinshagen, Braunschweig, 23.12.2016


Molecular pathological classification of colorectal cancer
Müller, Ibrahim, Arends, Virchows Arch (2016) 469:125–134
Kommentar: Prof. Dr. Andrea Tannapfel, Bochum, 23.12.2016


Do colorectal cancer patients diagnosed as an emergency differ from non-emergency patients in their consultation patterns and symptoms? A longitudinal data-linkage study in England
Renzi C, et al., Br J Cancer. 2016;115:866-875
Kommentar: Prof. Dr. R. Porschen, Bremen, 15.12.2016


Magnified endoscopic observation of early colorectal cancer by linked color imaging with crystal violet staining
T.Suzuki, T.Hara, Y.Kitagawa, T.Yamaguchi; Gastrointest.Endosc. 2016; 84:726-729
Kommentar: Dr. David Albers, PD Dr. Brigitte Schumacher, Essen, 30.11.2016


Colorectal cancer mortality reduction is associated with having at least 1 colonoscopy within the previous 10 years among a population-wide cohort of screening age
Stock, D; Paszat, F; Rabeneck, L; Gastrointestinal Endoscopy, 2016, 84
Kommentar: Prof. Dr. Dietmar Lorenz, Offenbach, 27.10.2016


Low-residue versus clear liquid diet before colonoscopy: a meta-analysis of randomized, controlled trials
Nguyen et al., Gastrointest Endosc (2016) vol. 83 (3) pp. 499-507
Kommentar: F. Berreth, Prof. Dr. W.G. Zoller, Stuttgart, 13.10.2016


A comparison of endoscopy versus pathology sizing of colorectal adenomas and potential implications for surveillance colonoscopy
JL Taylor,  HG Coleman, RT Gray, et al. Gastrointestinal Endoscopy 2016: 84: 341-351
Kommentar: Prof. Dr. Hendrik Bläker, Berlin, 10.10.2016


Genomic Alterations Observed in Colitis-Associated Cancers Are Distinct From Those Found in Sporadic Colorectal Cancers and Vary by Type of Inflammatory Bowel Disease
Rona Yaeger, Manish A. Shah, Vincent A. Miller, Judith R. Kelsen, Kai Wang, Zachary J. Heins, Jeffrey S. Ross, Yuting He, Eric Sanford, Rhonda K. Yantiss, Sohail Balasubramanian, Philip J. Stephens, Nikolaus Schultz, Moshe Oren, Laura Tang und David Kelsen, Gastroenterology. 2016; 151: 278-287.
Kommentar: Prof. Dr. med. Raja Atreya; Erlangen, 09.10.2016


Immunochemical fecal occult blood testing to screen for colorectal cancer:
Can the screening interval be extended?
Haug et al, GUT.2016; http://dx.doi.org/10.1136/gutjnl-2015-310102
Kommentar: Prof. Dr. Gabriela Möslein, Wuppertal, 26.09.2016


Colorectal cancer on the decline – why screening can’t explain it all
HG Welch, DJ Robertson; N Engl J Med 2016;374:1605-1607
Kommentar: Prof. Dr. Rainer Porschen, Bremen, 15.09.2016


Narrow-band Imaging International Colorectal Endoscopic Classification to predict polyp histology: REDEFINE study (with videos)
Alessandro Repici und Mitarbeiter; GASTROINTESTINAL ENDOSCOPY 84: 479-486 (2016)
Kommentar: Prof. Dr. Andrea Tannapfel, Bochum, 13.09.2016


Voluntary Running Suppresses Tumor Growth through Epinephrine- and IL-6-Dependent NK Cell Mobilization and Redistribution
Pedersen-L et al (2016) Cell Metabolism 23, 554–562.
Kommentar: Prof. Dr. Karen Steindorf, Heidelberg, 12.09.2016


Efficacy and safety of endoscopic resection of large colorectal polyps: a systematic review and meta-analysis
Hassan C, Repici A, Sharma P, et al. Gut 2016 ; 65 : 806-820
Kommentar: Prof. Dr. Michael Jung, Mainz, 06.09.2016


Clinical and endoscopic predictors of cytological dysplasia or cancer in a prospective multicenter study of large sessile serrated adenoms/polyps
Nicholas G Burgess, Maria Pellise, Kavinderjit S Nanda, Luke F Hourigan, Simon A Zanati, Gregor J Brown, Rajvinder Singh, Stephen J Williams, Spiro C Raftopoulos, Donald Ormonde, Alan Moss, Karen Byth, Heok P Ng, Duncan McLeod, Michael J Bourke; Burgess NG, et al. Gut 2016;65:437-446
Kommentar: Dr. Rainer Bastian, PD. Dr. Brigitte Schumacher, Essen, 19.08.2016


A Risk-Scoring System Combined With a Fecal Immunochemical Test is Effective in Screening High-Risk Subjects for Early Colonoscopy to Detect Advanced Colorectal Neoplasms
H-M Chiu, J Y.L. Ching, K. Chun Wu, R. Rerknimitr, J. Li, D. Wu, K. L. Goh, T. Matsuda, H. Kim, R. Leong, K. G. Yeoh, V. H. Chong, JH. D. Sollano, F. Ahmed, J. Menon and J.Y. Sung for the Asia-Pacific Working Group on Colorectal Cancer. Gastroenterology 2016;150:617-625
Kommentar: Prof. Dr. Karlheinz Beckh, Dr. Wolfgang Rimili, Worms, 11.08.2016


Development and validation of the WASP classification system for optical diagnosis of adenomas, hyperplastic polyps and sessile serrated adenomas/polyps
IJspeert et al., Gut. 2016; 65:963-70.
Kommentar: Prof. Dr. Andrea Tannapfel, Bochum, 04.07.2016


Aiming High — Changing the Trajectory for Cancer
Douglas R. Lowy, M.D., and Francis S. Collins, M.D., Ph.D. N Engl J Med 2016; 374:1901-1904 May 19, 2016DOI: 10.1056/NEJMp1600894
Kommentar: Prof. Dr. Markus F. Neurath, Erlangen, 28.06.2016


Preoperative indicators of failure of en bloc resection or perforation in colorectal endoscopic submucosal dissection: implications for lesion stratification by technical difficulties during stepwise training.
Imai, K. et al.; Gastrointestinal endoscopy 2016; 83:954-62
Kommentar: PD Dr. med. Siegbert Faiss, 19.06.2016


A novel self-propelled disposable colonoscope is effective for colonoscopy in humans.
Nathan Gluck, MD, PhD,1,2 Alaa Melhem, MD,1,2 Zamir Halpern, MD,1,2 Klaus Mergener, MD,3 Erwin Santo, MD
Kommentar: Dr. M. Knabe, Prof. Dr. C. Ell, 13.06.2016


Fecal immunochemical test program performance over 4 rounds of annual screening. A retrospective cohort study.
Jensen CD, Corley DA, Quinn VP, et al., Ann Int Med 2016;164:456-463
Kommentar: Prof. Dr. Thomas Frieling, Krefeld, 16.05.2016


Colonoscopy surveillance after colorectal cancer resection: recommendations of the US multi-society task force on colorectal cancer.
Charles J Kahi et al (2016) Gastrointestinal Endoscopy 83,3 :489-498
Kommentar: Prof. Dr. med. Werner Hohenberger, Erlangen; 12.05.2016


Quantification of Adequate Bowel Preparation for Screening or Surveillance Colonoscopy in Men
Clark BT et al. Gastroenterology 2016;150:396-405
Kommentar: PD Dr. med. Dirk Hartmann, Berlin; 09.05.2016


Role of cold biopsy technique in diminutive and small colonic polyp removal: a systematic review and meta‐analysis
Raad et al., Gastrointest Endosc 2016; 83;508‐515
Kommentar: Prof. Dr. Jörg Albert, Frankfurt; 03.05.2016


Long-term lifestyle changes after colorectal cancer screening: randomised controlled trial
Berstad et al., Gut 08/2015
Kommentar: PD Dr. Georgia Schilling, Hamburg; 10.03.2016


Association between Body Mass Index and Mortality for Colorectal Cancer Survivors: Overall and by Tumor Molecular Phenotype
Campbell P.T et al, Cancer Epidemiol Biomarkers Prev., 2015, 24(8):1229-38
Kommentar: Prof. Dr. Cornelia Ulrich und Caroline Himbert, Salt Lake City, 09.03.2016


Obesity and metabolic syndrome: pathological effects on the gastrointestinal tract
Feakins R.M., Histopathology 2015, 10.1111/his.12907
Kommentar: Prof. Dr. Cornelia Ulrich und Caroline Himbert, Salt Lake City, 09.03.2016


Aspirin and colorectal cancer: the promise of precision chemoprevention
Drew D.A et al, Nat Rev Cancer, 2016, 16(3):173-86
Kommentar: Prof. Dr. Cornelia Ulrich und Caroline Himbert, Salt Lake City, 03.03.2016


Aspirin use after diagnosis but no prediagnosis improves established colorectal cancer survival: a meta-analysis
Li P. et al, Gut. 2015, 64(9):141925.
Kommentar: Prof. Dr. Cornelia Ulrich und Caroline Himbert, Salt Lake City, 03.03.2016


Incidence and Mortality of Colorectal Cancer in Individuals with a Family History of Colorectal Cancer
Robert E. Schoen, Anthony Razzak, Kelly J. Yu, Sonja I. Berndt, Kevin Firl, Thomas L. Riley, and Paul F. Pinsky, Gastroenterology 2015; 149: 1438 – 1445
Kommentar: PD Dr. med. Brigitte Schumacher; Essen; 03.03.2016


Derivation and Validation of a Scoring System to Stratify Risk for Advanced Colorectal Neo-plasia in Asymptomatic Adults
Thomas F. Imperiale et al.; Ann Int Med 2015; 163:339-346
Kommentar: PD Dr. med. Siegbert Faiss; Hamburg; 11.01.2016


Systematic review with meta-analysis: the risk of gastrointestinal haemorrhage post-polypectomy in patients receiving anti-platelet, anti-coagulant and/or thienopyridine medications
D. Shalman & L. B. Gerson
Kommentar: Prof. Dr. med. Dr. h. c. W. G. Zoller, Stuttgart, 05.01.2016

2015


Longer Withdrawal Time Is Associated With a Reduced Incidence of Interval Cancer After Screening Colonoscopy
Shaukat A, Rector TS, Church TR, Lederle FA, Kim AS, Rank JM, Allen JI
Gastroenterology 2015;149:952-57
Kommentar: Prof. Dr. Ralf Jakobs, Ludwigshafen, 28.12.2015


Commensal Bifidobacterium promotes antitumor immunity and facilitates anti-PD-L1 efficacy
Sivan et al., Science 11/2015
Kommentar: PD Dr. Georgia Schilling, Freiburg, 06.12.2015


Genetics and Genetic Biomarkers in Sporadic Colorectal Cancer
Epigenetic Alterations in Colorectal Cancer: Emerging Biomarkers
Genetics and Genetic Testing in Hereditary Colorectal Cancer
John Carethers und Barbara Jung, Gastroenterology. 2015 Oct;149(5):1177-1190.
Yoshinaga Okugawa und Ajay Goel, Gastroenterology. 2015 Oct;149(5):1204-1225.
Elena Stoffel und Richard Boland, Gastroenterology. 2015 Oct;149(5):1191-1203
Kommentar: Dr. Timo Rath, Prof. Dr. Markus Neurath, Erlangen, 18.11.2015


Clinicopathological and molecular features of sessile serrated adenomas with dysplasia or carcinoma
Mark Bettington et al., Gut 2015;0:1–10. doi:10.1136/gutjnl-2015-310456
Kommentar: Prof. Dr. Andrea Tannapfel, Bochum, 16.11.2015


Periprocedural management of aspirin during colonoscopy: a survey of practice patterns in the United States
Robbins et al. Gastrointestinal Endoscopy 82, 895-900, 2015
Kommentar: Prof. Dr. Max Reinshagen, Braunschweig, 15.11.2015


Evaluation of the clinical efficacy of colon capsule endoscopy in the detection of lesions of the colon: prospective, multicenter, open study
Yutaka Saito, Shoichi Saito, Shiro Oka, Yasuo Kakugawa, Minori Matsumoto, Hiroyuki Aihara, Ikue Watari, Taiki Aoyama, Sadaharu Nouda, Takanori Kuramoto, Kenji Watanabe, Naoki Ohmiya, Kazuhide Higuchi, Hidemi Goto, Tetsuo Arakawa, Shinji Tanaka, Hisao Tajiri
Gastrointestinal Endoscopy 2015
Kommentar: Prof. Dr. med. Jörg Albert, Frankfurt, 03.11.2015


Physician report cards and implementing standards of practice are both significantly associ-ated with improved screening colonoscopy quality
Keswani RN et a. Am J Gastroenterol 2015; 110: 1134-1139
Kommentar: Prof. Dr. med. M. Jung FRCP, Mainz, 03.11.2015


Trends in Adenoma Detection Rates During the First 10 Years of the German Screening Colonoscopy Program
Brenner et al., Gastroenterology 2015;149:356-366
Kommentar: Prof. Dr. med. Helmut Neumann, Erlangen, 12.10.2015


Surveillance colonoscopy in low-risk postpolypectomy patients: Is it necessary?
Thomas A Hornung, Roisin Bevan, Saqib Mumtaz, Benjamin R Hornung, Matthew D Rutter. Frontline Gastroenterology 2014;0:1–8. doi:10.1136/flgastro-2014-100524
Kommentar: PD Dr.med. Albrecht Hoffmeister, Leipzig, 15.09.2015


Split-Dose Preparations Are Superior to Day-Before Bowel Cleansing Regimens: A Meta-analysis
Martel M et al. Gastroenterology 2015;149:79-88
Kommentar: PD Dr. med. Dirk Hartmann, Berlin, 14.9.2015


Higher adenoma recurrence rate after left- versus right-sided colectomy for colon cancer
Lorenzo Fuccio et al., Gastrointestinal Endoscopy 82, 2:2015, 337-343
Kommentar: Prof. Dr. W. Hohenberger, Erlangen, 10.09.2015


Investigating endoscopic features of sessile serrated adenomas/polyps by using nar-row-band imaging with optical magnification
Yamada et al.; Gastrointest Endosc 2015;82:108-117
Kommentar: Prof. Dr. Andrea Tannapfel, Bochum, 01.09.2015


Rezidivrate nach endoskopischer Resektion (EMR) von großen (<2cm) serratierten Adenomen
Douglas Rex, Gastrointest Endosc 2015;82:538-41
Kommentar: PD Dr. Axel Eickhoff, Hanau, 21.8.2015


Metachronous colorectal cancers result from missed lesions and non-compliance with surveillance
C. M. C. le Clercq, B. Winkens, C. M. Bakker, E. T. P. Keulen, G. L. Beets, A. M. Masclee, S. Sanduleanu; Gastrointest Endosc 2015; 82:325-33
Kommentar: Dr. Rainer Bastian, PD. Dr. Brigitte Schumacher, Essen, 19.8.2015


Variation in Adenoma Detection Rate and the Lifetime Benefits and Cost of Colorectal Cancer Screening. A Microsimulation Model.
R G S Meester, C A Doubeni, I Lansdorp-Vogelaaart, C D Jensen, M P van der Meulen, T R Levin, V P Quinn, J E Schottiner, A G Zauber, D A Corley, M van Ballegooijen. JA-MA.2015;313(23):2349-2358:
Kommentar: Dr. W. Rimili, Prof. Dr. med Karlheinz Beckh, Worms, 18.8.2015


Colon Capsule Versus CT Colonography in Patients with incomplete Colonoscopy
Cristiano Spada, Cesare Hassan, Brunella Barbaro, Franco Iafrate, Paola Cesaro, Lucio Pet-ruzziello, Leonardo Minelli Grazioli, Carlo Senore, Gabriella Brizi, Isabella Costamagna, Giu-seppe Alvaro, Marcella Iannitti, Marco Salsano, Maria Ciolina, Andrea Laghi, Lorenzo Bonomo, Guido Costamagna; GUT 2015;64:272-281.
Kommentar: Dr. med. Christian Pox, Bochum, 13.8.2015


Impact on colorectal cancer mortality of screening programmes based on the faecal immunochemical test
Manuel Zorzi, Ugo Fedeli, Elena Schievano, Emanuela Bovo, Stefano Guzzinati, Susanna Baracco,Ciara Fedato, Mario Saugo, Angelo Paolo Dei Tos; GUT 2015; 64: 784-790
Kommentar: Prof. Dr. Ulrich R. Fölsch, Kiel, 28.07.2015


Evaluation of a risk index for advanced proximal neoplasia of the colon
Ruco A, Stock D, Hilsden RJ, McGregor SE, Paszat LF, Saskin R, Rabeneck L.
Gastrointest Endosc. 2015; 81:1427-32
Kommentar: Prof. Dr. med. Raja Atreya, Erlangen, 16.7.2015


Effectiveness, training and quality assurance of colonoscopy screening for colorectal cancer
Robertson DJ et al. Gut 2015;64:982-990
Kommentar: PD Dr. med. Dirk Hartmann, Berlin, 15.7.2015


Serrated Lesions in Colorectal Cancer Screening
East et al.: Gut 2015;64:991-1000
Kommentar: Prof. Dr. Andrea Tannapfel, Bochum, 21.06.2015


Screening des kolorektalen Karzinoms mittels fäkaler immunochemischer Teste (FIT)
Auge et al., Gastroenterology 2014;147:628- 636
Kommentar: Prof. Dr. med. R. Porschen, Bremen 19.06.2015


Midlife Cardiorespiratory Fitness, Incident Cancer, and Survival After Cancer in Men. The Cooper Center Longitudinal Study (CCLS)
Lakoski et al., JAMA Oncol 03/2015
Kommentar: PD Dr. Georgia Schilling, Prof. Dr. Dirk Arnold, Klinik für Tumorbiologie, 10.06.2015


Impact of Retroflexion vs. Second Forward View Examination of the Right Colon on Adeno-ma Detection: A comparison Study
Kushnir et al., Am J Gastroenterol 2015;110:415-422
Kommentar: PD Dr. med. Dirk Hartmann, Berlin, 5.6.2015


Evaluation of mucosal healing in ulcerative colitis by fecal calprotectin vs. fecal immunochemical test
Takashima S, kato J, Hiraoka S, et al., Am J Gastroenterol online publication 31 March 2015
Kommentar: Prof. Dr. med. M. Jung FRCP, Mainz, 5.6.2015


Gut microbiome development along the colorectal adenoma-carcinoma sequence
Feng Q, Liang S, Jia H, Stadlmayr A, Tang L, Lan Z, Zhang D, Xia H, Xu X, Jie Z, Su L, Li X, Li X, Li J, Xiao L, Huber-Schönauer U, Niederseer D, Xu X, Al-Aama JY, Yang H, Wang J, Kristiansen K, Arumugam M, Tilg H, Datz C, Wang J. Nature Communications 11 Mar 2015
Kommentar: Prof. Dr. Andreas Stallmach, Jena, 29.5.2015


Expected long-term impact of the German screening colonoscopy programme on colorectal cancer prevention: Analyses based on 4,407,971 screening colonoscopies
Brenner H, Altenhofen L, Stock C, Hoffmeister M, Eur J Cancer 2015
Kommentar: Prof. Dr. Thomas Frieling, Krefeld,15.5.2015


Risk of Colorectal Cancer and Adenomas in the Families of Patients With Adenomas, A Population-Based Study in Utah
Therese M.F. Tuohy, PhD; Kerry G. Rowe, MS; Geraldine P. Mineau, PhD; Richard Pimen-tel, MS; Randall W. Burt, MD; and N. Jewel Samadder, MD, MSc, Cancer. 2014 Jan 1;120 (1):35-42
Kommentar: Dr. med. Rainer Bastian, PD. Dr. med. Brigitte Schumacher, Essen, 8.5.2015


Pre- and Postdiagnosis Physical Activity, Television Viewing, and Mortality Among Patients With Colorectal Cancer in the National Institutes of Health-AARP Diet and Health Study
Arem et al., Januar 2015, J Clin Oncol
Kommentar: PD Dr. Georgia Schilling, Prof. Dr. Dirk Arnold, Klinik für Tumorbiologie, 26.04.2015


Cancers complicating inflammatory bowel disease
Laurent Beaugerie L, Steven H. Itzkowitz. N Engl J Med. 2015;372:1441-52.
Kommentar: Prof. Dr. med. Markus F. Neurath und Prof. Dr. med. Raja Atreya, Erlangen, 25.04.2015


Genetic and Environmental Risk Assessment and Colorectal Cancer Screening in an Average-Risk Population: A Randomized Trial.  
David S. Weinberg, Ronald E. Myers, Eileen Keenan et al.
Ann Intern Med. 2014;161(8):537-545. doi:10.7326/M14-0765
Kommentar: Professor Dr. Dr.h.c. W.G.Zoller, Dr. Kay-Karsten Kober, Stuttgart, 10.04.2015


Local recurrence after endoscopic mucosal resection of nonpedundculated colorectal lesions: systematic review and meta-analysis.
Standardized long-term follow-up after endoscopic resection of large, nonpedunculated colorectal lesions: a prospective two-center study.
Belderbos TDG, Leenders M, Moon LMG, Siersema PD, Endoscopy 2014;46:388-400
Knabe M, Pohl J, Gerges CA, et al,; Am J Gastroenterol 2014;109:183-189
Kommentar: Prof. Dr. med. R. Porschen, Bremen, 02.04.2015


Vegetarian Dietary Patterns and Mortality in Adventist Health Study 2
M. J. Orlich et al, JAMA Intern Med. 173: 1230-1238 (2013)
Kommentar: Prof. Dr. med. Christian Löser, Kassel, 02.04.2015


Accuracy of capsule Colonoscopy and Computed Tomographic Colonography in Individuals with Positive Results from the Fecal Occult Blood test
Rondonotti et al.; Clinical Gastroenterology and Hepatology 2014; 12:1303-1310;. Kommentar: PD Dr. med. Siegbert Faiss; Hamburg, 25.03.2015


Quality Indicators for GI Endoscopic Procedures
Am J Gastroenterol 2015; 110:72–90; doi: 10.1038/ajg.2014.385;
Kommentar: Dr. med. Rainer Bastian, PD. Dr. med. Brigitte Schumacher, Essen, 06.03.2015


Colon and Endometrial Cancers with Mismatch Repair Deficiency can arise from Somatic, rather than germline mutations
Gastroenterology 2014;147:1308-1316.
Kommentar: Dr. Timo Rath, Prof. Dr. Markus Neurath; Erlangen, 06.03.2015


Prevention, Early Detection, and Overdiagnosis of Colorectal Cancer Within 10 Years of Screening Colonoscopy in Germany.
Clin Gastroenterol Hepatol. 2014 Sep 15. pii: S1542-3565(14)01313-5. doi: 10.1016 /j.cgh.2014.08.036.
Kommentar: PD Dr. Axel Eickhoff, Hanau, 23.02.2015


Association Between Molecular Subtypes of Colorectal Cancer and Patient Survival.
Phipps et al., Gastroenterology (Januar 2015).
Kommentar: Priv.-Doz. Dr. Georgia Schilling, Prof. Dr. Dirk Arnold, Klinik für Tumorbiologie, 13.02.2015


Low Rate of Large Polyps (9 mm) Within 10  Years After an Adequate Baseline Colonoscopy With No Polyps.
David A.Liebermann,Jennifer L. Holub,Cynthia D. Morris,Judith Logan, J. Lucas Williams and Patricia Carney.
Kommentar: Prof. Dr. Ulrich R. Fölsch, Generalsekretär der Deutschen Gesellschaft für Innere Medizin (DGIM), 06.02.2015


Cathelicidin suppresses colon cancer development by inhibition of cancer associated fibroblasts.
Cheng et al.;
Kommentar: Prof. Dr. Thomas Seufferlein, Ulm, 30.1.2015



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2014


Risk factors for colorectal neoplasia in persons aged 30 to 39 years and 40 to 49 years.
Jung Y.S. et al.; Gastrointest Endosc  2014 doi.org/10.1016/j.gie.2014.09.031
Kommentar: PD Dr. med. Siegbert Faiss; Asklepios Klinik Barmbek, Hamburg, 27.12.2014


Sessile Serrated Polyps at Screening Colonoscopy: Have They Been Under Diagnosed ? Tinmouth et al. Am J Gastroenterol 2014; 109:1698–1704
Kommentar: Prof. Dr. med. Andrea Tannapfel, Ruhruniversität Bochum, 20.12.2014


The incidence of advanced neoplasia after polypectomy in patients with and without low-risk adenomas. Hassan C, Gimeno-Garcia A, Kalager M et al
Kommentar: Prof. Dr. med. Joachim Mössner, Universitätsklinikum Leipzig, 14.12.2014


Prediagnostic Lifestyle Factors and Survival After Colon and Rectal Cancer Diagnosis in the National Institutes of Health (NIH)-AARP Diet and Health Study
Pelser et al., Cancer (May 2014)
Kommentar: PD Dr. Georgia Schilling, Prof. Dr. Dirk Arnold, Klinik für Tumorbiologie, 06.12.2014


Association between physical activity and mortality in colorectal cancer: a meta-analysis of prospective cohort studies. (Zusammenhang von körperlicher Betätigung und Sterblichkeit beim kolorektalen Karzinom: Eine Metaanalyse prospektiver Kohortenuntersuchungen)
Je Y, Jeon JY, Giovannucci EL, Meyerhardt JA. Int J Cancer. 2013 Oct 15;133(8):1905-13.
Kommentar: Prof. Dr. Marco Sailer, Klinik für Chirurgie, Bethesda KH Bergedorf, Hamburg, 03.12.2014


Increasing Disparities in the age-related Incidences of Colon and Rectal Cancers in the United States 1975 – 2010
Bailey et al.  JAMA Surgery  (online 5 November 2014)
Kommentar: Prof. Dr. M. Reinshagen, Medizinische Klinik I, Klinikum Braunschweig, 11.11.2014


Race, Ethnicity, and Sex Affect Risk for Polyps >9 mm in Average-Risk Individuals
Gastroenterology 2014;147:351–358
Kommentar: PD Dr. Axel Eickhoff, Medizinische Klinik II, Klinikum Hanau, 21.10.2014


Impact on colorectal cancer mortality of screening programmes based on the faecal immu-nochemical test
Manuel Zorzi, Ugo Fedeli, Elena Schievano, Emanuela Bovo, Stefano Guzzinati, Susanna Baracco, Chiara Fedato, Mario Saugo, Angelo Paolo Dei Tos, publiziert in Gut. 2014 Sep 1. pii: gutjnl-2014-307508. doi: 10.1136/gutjnl-2014-307508
Kommentar: PD Dr.med. Albrecht Hoffmeister, Universitätsklinikum Leipzig, 17.10.2014


Surveillance Colonoscopy in Elderly Patients“ – A Retrospective Cohort Study
An Hong Tran, Eunis Wai Man Ngor, Bechien U Wu, publiziert in JAMA 2014
Kommentar: Prof. Dr. med. Dr. h.c. Werner Hohenberger, Chirurgische Klinik, Universitätsklinikum Erlangen, 02.10.2014


Alkohol und Adenome Zhu APT 2014, Alimentary Pharmacology and Therapeutics
Alkohol und Adenome Zhu APT 2014
Kommentar: Dr. Christian Pox, Ruhr-Universität Bochum, Knappschaftskrankenhaus Bochum, 23.09.2014


Long-Term Colorectal-Cancer Mortality after Adenoma Removal
Løberg M et al. N Engl J Med 2014;371:799-807; doi: 10.1056/NEJMoa1315870
Kommentar: Prof. Dr. med. M. Jung, Katholisches Klinikum Mainz, 09.09.2014


Einfluss von Bewegung und Gewichtsreduktion bei adipösen Adenompatienten
Anderson AS et al. BMJ 2014;348:1823
Kommentar: Prof. Dr. Dieter Schilling, Diakonie-Krankenhaus, Medizinische Klinik II, Mannheim, 03.09.2014


Ist eine Neubewertung von Stuhltests in der Darmkrebsvorsorge erforderlich?
Shaukat A et al, N Engl J Med 2013;369:1106-1114; Logan FA et al, Gut 2012;61:1439-1446; Brenner H et al, Int J Cancer 2014;134(12):2927-2934; Lee JK et al, Ann Intern Med 2014;160:171-181
Kommentar: Prof. Dr. med. Wolfgang Fischbach, Medizinische Klinik II und Klinik für Palliativmedizin, Klinikum Aschaffenburg, 01.09.2014


Long-Term Colorectal-Cancer Mortality after Adenoma Removal
Løberg M, Kalager M, Holme Ø, Hoff G, Adami H, Bretthauer, M. N Engl J Med 2014; 371: 799-807
Kommentar: Prof. Dr. med Karlheinz Beckh, Dr. med Wolfgang Rimili, Medizinische Klinik II, Klinikum Worms gGmbH, Worms, 11.09.2014


Characteristics of missed or interval colorectal cancer and patient survival:
a population-based study
Samadder NJ, Curtin K, Tuohy TMF, et al. Gastroenterology 2014;146:950-960
Kommentar: Prof. Dr. med. R. Porschen, Klinik für Innere Medizin, Klinikum Bremen-Ost, 27.08.2014


A score to estimate the likelihood of detecting advanced colorectal neoplasia at coloskopie
M F Kaminski, M Polkowski, E. Kraszewska, M. Rupinski, E. Butruk, J. Regula
Kaminski MF, et al. Gut 2014; 63:1112-1119.
Kommentar: Dr. med. Rainer Bastian, PD. Dr. med. Brigitte Schumacher, Elisabeth Krankenhaus Essen, 16.08.2014


Cold snare polypectomy vs. Cold forceps polypectomy using double-biopsy technique for removal of diminutive colorectal polyps: a prospective randomized study.
Lee CK1, Shim JJ, Jang JY. Am J Gastroenterol. 2013 Oct;108(10):1593-600.
doi: 0.1038/ajg.2013.302. Epub 2013 Sep 17.
Kommentar: PD Dr. med. Axel Eickhoff, Medizinische Klinik II, Klinikum Hanau 11.07.2014


Postcolonoscopy colorectal cancers are preventable: a population-based study
Le Clerq CMC et al.; Gut 2014;63:957-963
Kommentar: PD Dr. med. Siegbert Faiss; Asklepios Klinik Barmbek, Gastroenterologie & Interventionelle Endoskopie, Rübenkamp 220, 22291 Hamburg; 18.07.2014


Proximal and distal colorectal cancer resection rates in the United States since widespread screening by colonoscopy.
Myer et al. Gastroenterology. 2012 Nov;143(5):1227-36.
Kommentar: Dr. Alexander Hann, Facharzt für Innere Medizin, Klinik für Allgemeine Innere Medizin, Gastroenterologie, Hepatologie und Infektiologie, Katharinenhospital Stuttgart und Professor Dr. med. Dr. h.c. W. G. Zoller, Ärztlicher Direktor der Klinik für Allgemeine Innere Medizin, Gastroenterologie, Hepatologie, Infektiologie und Pneumologie, Katharinenhospital Stuttgart und Leiter des Zentrums für Innere Medizin Klinikum Stuttgart; 06.06.2014


Intervallkarzinome
Incomplete Polyp Resection During Colonoscopy—Results of the Complete Adenoma Resection (CARE) Study, Pohl, H. et al.; Gastroenterology 2013;144:74–80
Kommentar: PD Dr. med. Siegbert Faiss, Asklepios Klinik Barmbek, Hamburg; 11.04.2014


Endoskopische in-vivo versus histologische Charakterisierung von Polypen während einer Screening-Koloskopie
Endoscopic versus histological characterization of polyps during screening colonoscopy, Gut 2014;63:458-465
Kommentar: PD Dr. Axel Eickhoff, Medizinische Klinik II, Klinikum Hanau; 11.04.2014


Treffsicherheit von Fäkalen Immunchemischen Tests bei der Erkennung des kolorektalen Karzinoms
Lee JK, Liles EG, Bent S, Levin TR, Corley DA; Ann Intern Med 2014; 160:171-181
Kommentar: Prof. Dr. K. Beckh und Dr. W. Rimili, Medizinische Klinik II, Klinikum Worms; 31.03.2014


Reduced risk of colorectal cancer up to 10 years after screening, surveillance or diagnostic colonoscopy
Brenner et al., Gastroenterology 2014 (in press)
Kommentar: Prof. Dr. Max Reinshagen, Medizinische Klinik I, Klinikum Braunschweig, 04.03.2014


Superior diagnostic performance of faecal immunochemical tests for haemoglobin in a head-to-head comparision with guaiac based faecal occult blood test among 2235 participants of screening colonscopy
Brenner H, Tao S. Europ. J. Cancer 2013;49:3049-3054
Kommentar: Prof. Dr. R. Porschen, Klinik für Innere Medizin, Klinikum Bremen-Ost, 11.02.2014


Lower Endoscopy Reduces Colorectal Cancer incidence in Older Indivduals
Erichsen, R. et al.; Am J Gastroenterol 2013;108:1332-1340
Kahi, C.J. et al.; Gastroenterology 2014 (doi.org/10.1053/j.gastro.2013.11.050)
Kommentar: PD Dr. Siegbert Faiss; Asklepios Klinik Barmbek, 04.02.2014


Computed tomographic colonography versus colonoscopy for investigation of patients with symptoms suggestive of colorectal cancer (SIGGAR): a multicentre randomised trial
Atkin et al. Lancet 381, 1194-1202, 2013-12-27
Kommentar: Prof. Dr. Max Reinshagen, Medizinische Klinik I, Klinikum Braunschweig, 13.01.2014



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2013


Characteristics and Survival of Interval and Sporadic Colorectal Cancer Patients: A Nationwide Population-Based Cohort Study
Erichsen, R. et al.; Am J Gastroenterol 2013;108:1332-1340
Kommentar: PD Dr. Siegbert Faiss; Asklepios Klinik Barmbek, 20.11.2013


Advanced Adenoma Detection Rate Is Independent of Nonadvanced Adenoma Detection Rate / Die Detektionsrate für fortgeschrittene kolorektale Adenome ist unabhängig von der Gesamtdetektionsrate nicht-fortgeschrittener kolorektaler Adenome
Am J / Gastroenterol 2013;108:1286-1292
Kommentar: PD Dr. Axel Eickhoff, Medizinische Klinik II, Klinikum Hanau, 23.10.2013


Long-Term Mortality after Screening for Colorectal Cancer
Autoren: Reiko Nishihara, Kana Wu, Paul Lochhead, Teppei Morikawa, Xiaoyun Liao, Zhi Rong Qian, Kentaro Inamura, Sun A.Kim, Aya Kuchiba, Mai Yamauchi, Yu Imamura, Walter C.Willett, Bernard A. Rosner, Charles S. Fuchs, Edward Giovannucci, Shuji Ogino, Andrew T. Chan Shaukat, A et al. (2013) / N Engl J Med 369;12
Kommentar: Prof. Dr. Wolfram G. Zoller, Klinikum Stuttgart, 08.10.2013


Long-term colorectal-cancer incidence and mortality after lower endoscopy
Autoren: Reiko Nishihara, Kana Wu, Paul Lochhead, Teppei Morikawa, Xiaoyun Liao, Zhi Rong Qian, Kentaro Inamura, Sun A.Kim, Aya Kuchiba, Mai Yamauchi, Yu Imamura, Walter C.Willett, Bernard A. Rosner, Charles S. Fuchs, Edward Giovannucci, Shuji Ogino, Andrew T. Chan / The New England Journal of Medicine 2013;369,NO.12:1095-1105
Kommentar: PD Dr. Brigitte Schumacher, Elisabeth-Krankenhaus Essen (ab 1.11.13), 28.09.2013


Variabilität der Nachsorgeintervalle nach erster Screeningkoloskopie
Autoren: Stock C, Hoffmeister M, Birkner B, Brenner H. / Interphysician variation in follow-up colonoscopies after screening colonoscopy / PLoS ONE 2013;8(7):e69312.doi:10.1371 / journal.pone.0069312
Kommentar: Prof. Dr. R. Porschen, Klinik für Innere Medizin, Klinikum Bremen-Ost, 13.08.2013


Superior diagnostic performance of faecal immunochemical tests for haemoglobin in a head-to-head comparison with guaiac based gaecal occult blood test among 2235 participants of screening coloscopy
Autoren: H. Brenner und S. Tao / European Journal of Cancer 2013
Kommentar: Prof. Dr. Gabriela Möslein, St. Josefs-Hospital, Bochum-Linden, 10.08.2013


Incomplete polyp resection during colonoscopy-results of the complete adenoma resection (CARE) study
Autoren: Heiko Pohl, Amitabh Srivastava, Steve P. Bensen, Peter Anderson, Richard I. Rothstein,Stuart R. Gordon, L. Campbell Levy, Arifa Toor, Todd A. Mackenzie, Thomas Rosch, Douglas, J. Robertson / Gastroenterology. 2013 Jan 144(1):74-80.e1
Kommentar: PD Dr.med. Albrecht Hoffmeister, Universitätsklinikum Leipzig, 17.07.2013


Time lag to benefit after screening for breast and colorectal cancer: meta-analysis of survival data from the United States, Sweden, United Kingdom and Denmark
Autoren: BMJ2013;346doi:http://dx.doi.org/10.1136/bmj.e8441 (Published 8 January 2013)
Kommentar: Prof. Dr. Ulrich R. Fölsch, Christian-Albrechts-Universität Kiel, 11.07.2013


Meta-analysis: colonoscopic post-polypectomy bleeding in patients on continued clopidogrel therapy
Autoren: Gandhi S et al.; Aliment Pharmacol Ther 2013; 37: 947-952

Kommentar: PD Dr. P. Gaßmann; Prof. Dr. H. Lang, Klinik für Allgemein-, Viszeral- und Transplantationschirurgie, Universitätsmedizin Mainz, 03.07.2013


Giant Inflatable Colon and Community Knowledge, Intention and Social Support for Colorectal Cancer Screening
Autoren: Redwood D, Provost E, Asay E, Ferguson J, Muller J./Prev Chronic Dis 2013;10:120192
Kommentar: Prof. Dr. K. Beckh und Dr. W. Rimili, Medizinische Klinik II, Klinikum Worms, 24.06.2013


Efficacy of a Nationwide Screening Colonoscopy Program for Colorectal Cancer
Autoren: Ch. Pox, L. Altenhofen, H. Brenner, A. Theilmeier, D. von Stillfried, W. Schmiegel
Gastroenterology 2012;142:1460-1467
Kommentar: Prof. Dr. Dr. h.c. W. Hohenberger, Chirurgische Klinik – Universitätsklinikum Erlangen, 10.06.2013


Computed tomographic colonography versus barium enema for diagnostic of colorectal cancer or large polyps in symptomatic patients (SIGGAR): a multicenter randomized trial
Autoren: Steve Halligan, Kate Wooldrage, Edward Dadswell, Ines Kralj-Hans, Christian von Wagner, Rob Edwards, Guiqing Yao, Clive Kay, David Burling, Omar Faiz, Julian Teare, Richard J Lilford, Dion Morton, Jane Wardle, Wendy Atkin, for SIGGAR investigators* / Lancet 2013;381:1185-93
Kommentar: PD Dr. Brigitte Schumacher, Evangelisches Krankenhaus Düsseldorf, 22.05.2013


Pathological reassessment of hyperplastic colon polyps in a city-wide pathology practice: implications for polyp surveillance recommendations
Autoren: Singh H et al, GIE (2012) 76:1003-1008
Kommentar: Prof. Dr. Michael Jung, Katholisches Klinikum Mainz, Akademisches Lehrkrankenhaus der Johannes Gutenberg-Universität Mainz, 08.05.2013


Physical activity and gastrointestinal cancer prevention
Autoren: Wolin KY, Tuchman H.; Recent Results Cancer Res. 2011; 186: 73-100
Physical activity and male colorectal cancer survival

Autoren: Meyerhardt JA, Giovannucci EL, Ogino S et al.;Arch Intern Med 2009; 169: 2102-2108
Kommentar: Prof. Dr. Christian Löser, Rotes Kreuz Krankenhaus Kassel, 17.04.2013


Primary prevention of colorectal cancer
Autoren: Hassan C. et al. Gut 2012:61; 1172-1179
Kommentar: Claudia Schneider und Professor Dr. Gabriela Möslein, St.-Josefs-Hospital, Bochum-Linden, 26.02.2013



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2012

Cell surface proteomics identifies glucose transporter type 1 and prion protein as candidate biomarkers for colorectal adenoma-to-carcinoma progression.
Autoren: de Wit M, Jimenez CR, Carvalho B, Belien JA, Delis-van Diemen PM, Mongera S, Piersma SR, Vikas M, Navani S, Pontén F, Meijer GA, Fijneman RJ.
Gut. 2012 Jun;61(6):855-64. Epub 2011 Sep 2.
Kommentar: Professor Dr. med. Helmut Neumann, Professor Dr. med. Markus F. Neurath, Medizinische Klinik I, Interventionelle Endoskopie, Universitätsklinikum Erlangen, 09.12.2012

Risk factors for advanced neoplasia within subcentimetric polyps: implications for diagnostic imaging
Autoren: Gut 2012;50:445-448
Kommentar: PD Dr. Axel Eickhoff, Medizinische Klinik II, Klinikum Hanau, 30.11.2012

Guidelines for Colonoscopy Surveillance after screening and Polypectomy: A Consensus update by the US Multi-Society Task Force on Colorectal cancer
Autoren: David A. Liebermann, Douglas K. Rex, Sidney J. Winawer, Francis M. Giardiello,David A. Johnson, and Theodore R. Levin, Gastroenterology 2012;143:844-57
Kommentar: Dr. med. Jean Pierre Charton und PD. Dr. med. Brigitte Schumacher, Evangelisches Krankenhaus Düsseldorf, 20.10.2012

Obesity, weight change, and risk of adenoma recurrence: a prospective trial
Autoren: Laiyemo AO, Doubeni C, Badurdeen DS, Murphy G, Marcus PM, Schoen RE, Lanza E, Smoot DT. – Endoscopy 2012; 44: 813–818
Kommentar: Professor Dr. K. Beckh und Dr. W. Rimili, Medizinische Klinik II, Klinikum Worms, 12.10.2012

Prevalence of adenomas and advanced in patients in the 40- to 49-year age group undergoing screening colonoscopy because of a family history of adenoma/Polyp in a first- degree relative
Autoren: Akshay Gupta, MD,1,4 Jewel Samadder, MD,1 Eric Elliott, MPH,1,2 Saurabh Sethi, MD,3 – Philip Schoenfeld, MD, MSEd, MSc (Epi)1,2
Kommentar: Professor Dr. Werner Hohenberger, Chirurgische Klinik mit Poliklinik, Universitätsklinikum Erlangen, 08.10.2012

The Joint Association of Eating Frequency and Diet Quality with Colorectal Cancer Risk in the Health Professionals Follow-up Study
Autor: Mekary R A, Hu F B, Willett W C, et al. Am J Epidemiol. 2012; 175:664-672
Kommentar: Professor Dr. med. R. Porschen, Klinik für Innere Medizin, Klinikum Bremen-Ost, 04.10.2012

Lifestyle Änderungen und Mobilität in adipösen Erwachsenen mit Typ 2 Diabetes
Autor: W. J. Rejeski et al., N Engl J Med 2012; 366(13):1209-1217
Kommentar: Professor Dr. Petra-Maria Schumm-Dräger, Städtisches Klinikum München-Bogenhausen, 15.09.2012

High colonoscopic prevalence of proximal colon serrated polyps in average – risk men and women
Autor: Kahi C, Li X, Eckert G, Rex DK Gastrointest Endosc 2012;75:515-20
Kommentar: Professor Dr. med. Dieter Schilling, Diakoniekrankenhaus Mannheim 03.09.2012

Colonoscopic polypectomy and long-term prevention of colorectal-cancer deaths
Autor: Ann G. Zauber, Ph.D., Sidney J. Winawer, M.D., Michael J. O’Brien, M.D., M.P.H.,Iris Lansdorp-Vogelaar, Ph.D., Marjolein van Ballegooijen, M.D., Ph.D.,Benjamin F.Hankey, Sc.D., Weiji Shi, M.S., John H. Bond, M.D., Melvin Schapiro, M.D., Joel F.Panish, M.D., Edward T. Stewart, M.D., and Jerome D. Waye, M.D. / N Engl J Med 2012; 366:687-696
Kommentar: Dr. med. T. Bösing und Professor Dr. med. Dr. h.c. W.- G. Zoller, Klinik für Allgemeine Innere Medizin, Gastroenterologie, Hepatologie und Infektiologie, Katharinenhospital, Klinikum Stuttgart, 10.07.2012

CO2 versus air insufflations for private practice routine colonoscopy: results of a randomized double blind trial
Autor: N.N. / Z Gastroenterol 2012;50:445-448
Kommentar: PD Dr. Axel Eickhoff, Medizinische Klinik II, Klinikum Hanau, 10.07.2012

Prevalence of advanced histological features in diminutive and small colon polyps.
Autor: Neil Gupta,MD,MPH, Ajay Bansal,MD, Deepthi Rao,MD, Gayna S.Early, MD, Sreenivasa Jonnalagadda,MD, Sachin B. Wani,MD, Steven A. Edmundowicz,MD, Prateek Sharma,MD, Amit Rastogi, MD / Gastrointestinal Endosc. 2012;75:1022- 30.
Kommentar: PD Dr. med. Brigitte Schumacher, EVK Düsseldorf, 29.05.2012

Participation and yield of colonoscopy versus non-cathartic CT colonography in population-based screening for colorectal cancer: a randomised controlled trial.
Autor/en: Stoop EM, de Haan MC, de Wijkerslooth TR, Bossuyt PM, van Ballegooijen M, Nio CY, van de Vijver MJ, Biermann K, Thomeer M, van Leerdam ME, Fockens P, Stoker J, Kuipers EJ, Dekker E. Lancet Oncol. 2012 Jan;13(1):55-64.
Kommentar: Professor Dr. med. Markus F. Neurath und Professor Dr. med. Helmut Neumann, Universitätsklinikum Erlangen, 24.04.2012

Participation in colorectal cancer screening trials after first-time invitation: a systematic review
C. Khalid-de Bakker, D. Jonkers, K. Smits, I. Mesters, A. Masclee,
R.Stockbrügger / Endoscopy 2011; 43: 1059–1086
Kommentar: Professor Dr. med. Ralf Kiesslich, Universitätsmedizin Mainz, 03.02.2012

Efficacy of Annual Colonoscopic Surveillance in Individuals With Hereditary Nonpolyposis Colorectal Cancer Autor: Engel C et al / Clin Gastroenterol Hepatol 2010;8;174-182 Prevalence of Adenomas and Colorectal Cancer in Average
Individual Risk Individuals: A Systematic Review and Meta-analysis. Autor: Heitman SJ et al / Clin Gastroneterol Hepatol 2009;7:1272
Kommentar zu zwei Arbeiten: Professor Dr. med. R. Porschen, Chefarzt der Klinik für Innere Medizin, Klinikum Bremen-Ost, 03.02.2012

Quality of colonoscopy performance among gastroenterology and surgical trainees: a need for common training standards for all trainees?
Autor: JE Leyden et al / Endoscopy 2011;42:935-940
Kommentar: Professor Dr. med. A.H. Hölscher, Direktor der Klinik und Poliklinik für Allgemein-, Viszeral- und Tumorchirurgie, Universitätsklinik Köln, 31.01.2012

Effect of daily aspirin on long-term risk of death due to cancer: analysis of individual patient data from randomised trials
Peter M Rothwell, F. Gerald R Fowkes, Hisao Ogawa, Charles P Warlow, Tom W Meade / Lancet. 2011 Jan 1; 377 (9759):31-41 / Published online December 6-2010
Kommentar: Professor Dr. Gabriela Möslein, St. Josefs-Hospital, Bochum-Linden, 10.01.2012

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2011

Cancer incidence in type 2 diabetes patients – first results from a feasibility study of the D2C cohort
Hans-Werner Hense, Hiltraud Kajüter, Jürgen Wellmann, Wolf U Batzler
Kommentar: Prof. Dr. Petra Maria Schumm-Draeger, München, 13.12.2011

How much colonoscopy screening should be recommended to individuals with various degrees of family history of colorectal cancer?
Wilschut JA, Steyerberg EW, van Leerdam ME, Lansdorp-Vogelaar I, Habbema JD, van Ballegooijen M. Cancer. 2011 Sep 15;117(18):4166-74.
Kommentar: Prof. Dr. med. Markus F. Neurath und Prof. Dr. med. Helmut Neumann, 08.12.2011

Miss rate of right-sided colon examination during colonoscopy defined by retroflexion: an observational study
Hewett DG, Rex DK. Gastrointestinal Endoscopy 2011;74:246-252
Kommentar: Prof. Dr. med. W. Fischbach, Medizinische Klinik II und Klinik für Palliativmedizin, Klinikum Aschaffenburg, 26.10.2011

Endoscopic Mucosal Resection Outcomes and Prediction of Submucosal Cancer From Advanced Colonic Mucosal Neoplasia
Moss A, Bourke MJ, Williams SJ, Hourigan LF, Brown G, Tam W, Singh R, Zanati S, Chen RY, Byth K
Kommentar: Dr. med. T. Bösing, Prof. Dr. med. Dr. h. c. W. G. Zoller. Klinik für Allgemeine Innere Medizin, Gastroenterologie, Hepatologie und Infektiologie, Katharinenhospital, Klinikum Stuttgart, 25.10.2011

An Alerting System Improves Adherence to Follow-up Recommendations From Colonoscopy Examinations
Leffler DA, Neeman N, Rabb JM, Shin JY, Landon BE, Pallav K, Falchuk ZM, Aronson MD. Gastroenterology 2011;140:1166-1173.
Kommentar: Prof. Dr. K. Beckh und Dr. W. Rimili, Medizinische Klinik II, Klinikum Wormsa, 24.10.2011

Five-year follow-up of the Medical Research Council CLASICC trial of laparoscopically assisted versus open surgery for colorectal cancer.
Jayne DG, Thorpe HC, Copeland J, Quirke P, Brown JM, Guillou PJ. British Journal of Surgery 2010 Nov;97(11):1638-45.
Kommentar: Prof. Dr. Marco Sailer, Klinik für Chirurgie, Bethesda Krankenhaus Bergedorf, Hamburg

Expected reduction of colorectal cancer incidence within 8 years after introduction of the German screening colonoscopy programme: Estimates based on 1.875.708 screening colonoscopies.
Brenner H, Hoffmeister M, Brenner G, Altenhofen L, Haug U Eur J Canc 2009; 45:2027-2033
Kommentar: Prof. Dr. K. Beckh, Dr. W. Rimili Medizinische Klinik II Klinikum Worms gGmbH, 21.01.2011

Protection from Right- and Left-Sided Colorectal Neoplasms After Colonoscopy: Population-Based Study.
Brenner H, Hoffmeister M, Arndt V, Stegmaier C, Altenhofen L, Haug U., J Natl Cancer Inst 2010; 102: 89-95
Kommentar: Prof. Dr. K. Beckh, Dr. W. Rimili Medizinische Klinik II Klinikum Worms gGmbH, 13.01.2011

Low risk of colorectal cancer and advanced adenomas more than 10 years after negative colonoscopy
Brenner H et al., Gastroenterology 2010; 138:870-876
Kommentar: Prof. Dr. Thomas Seufferlein, Universitätsklinikum Halle (Saale), Universitätsklinik und Poliklinik für Innere Medizin I, 06120 Halle (Saale), 20.11.2010
Kommentar: Prof. Dr. Dr. h. c. W. G. Zoller/Dr. J. Knapp, Katharinenhospital und Zentrum für Innere Medizin, Klinikum Stuttgart, 08.03.2011

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2010

A novel device for rapid cleaning of poorly prepared colons
Moshkowitz M et al.; Endoscopy 2010;42:824.36
Kommentar: Dr. Oliver Movadat / Prof. Dr. Markus F. Neurath, Medizinische Klinik 1, Universitätsklinikum Erlangen, 10.11.2010

Susceptibility Genetic Variants Associated With Colorectal Cancer Risk Correlate With Cancer Phenotype
Abuli A et al., Gastroenterology 2010;139:788-796
Kommentar: Dr. Oliver Movadat & Prof. Dr. Markus F. Neurath, Medizinische Klinik 1, Universitätsklinikum Erlangen, 10.11.2010

Anhaltendes Risiko für ein kolorektales Karzinom trotz Vorsorgekoloskopie: die Polyp Prevention Trial Continued Follow-up Studie (PPT-CFS)
Leung K, Pinsky P, Laiyemo AO, Lanza E, Schatzkin A: Gastrointest Endosc 2010; 71(1):111-7.
Kommentar: Prof. Dr. K. Beckh, Dr. W. Rimili Medizinische Klinik II Klinikum Worms gGmbH, 18.03.10

Aktueller Wissensstand der Bevölkerung zur Darmkrebsvorsorge – eine Untersuchung der Stiftung LebensBlicke mit dem Institut für Demoskopie in Allensbach
Wuppermann D., Wuppermann U, Riemann JF: Z. Gastroenterol 2009; 47; 1123-1136
Kommentar: Prof. Dr. W. G. Zoller, Katharinenhospital und Zentrum für Innere Medizin, Klinikum Stuttgart, 23.02.10

Hohe Akzeptanz der Darmspiegelung bei erstgradigen Verwandten von Patienten mit Kolonkarzinom in einer Region : eine populations-basierte, prospektive Studie
Armelao et al. Endoscopy 42, 15-21,2010
Kommentar: Prof. Dr. Max Reinshagen, Medizinische Klinik I, Städt. Klinikum Braunschweig gGmbH, 10.02.2010

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2009

“Das kolorektale Karzinom im Wandel der Zeit”
Benko et al.: Coloproctology 31, 283-290, 2009-11-21
Kommentar: Prof. Dr. Max Reinshagen, Medizinische Klinik I, Städt. Klinikum Braunschweig gGmbH, 25.11.09

“Incidence and predictors of “late” recurrences after endoscopic piecemeal resection of large sessile adenomas”.
Publikation von Khashab M, Eid E, Rusche M und Rex DK: Gastrointest Endosc. 2009; 70:344-9.
Kommentar: Prof. Dr. A.H. Hölscher, Klinik für Visceral- und Gefäßchirurgie, Universität Köln, 27.10.09

Kommentar im Deutschen Ärzteblatt zu einer Studie, die im World Journal of Gastroenterology 2009 veröffentlicht wurde.
(Barrier-focused intervention to increase colonoscopy (WorldJGastorenterol 2009-08-21-15(31):3920-3925)
Kommentar: Prof. Dr. K. Beckh, Dr. W. Rimili Medizinische Klinik II Klinikum Worms gGmbH, 26.10.09

Improved diagnosis of colorectal cancer using a combination of fecal occult blood and novel fecal protein parameters
Clin Gastroenetrology and Hepatology, 2008; 6:1122-1128
Kommentar: Prof. Dr. Thomas Seufferlein, Universitätsklinikum Halle (Saale), Universitätsklinik und Poliklinik für Innere Medizin I, 06120 Halle (Saale), 30.09.09

Increase in Incidence of Colorectal Cancer Among Young Men and Women in the United States; Cancer Epidemiol Biomarkers Prev 2009;18(6):1695–8);
Autor: Rebecca L. Siegel, Ahmedin Jemal, and Elizabeth M. Ward
Kommentar: Prof. Dr. Hauke Lang, Klinik für Allgemein- und Abdominalchirurgie, und PD Dr. Andreas D. Rink, Johannes Gutenberg-Universität Mainz, 21.09.09

Inhibition of Poly(ADP-Ribose) Polymerase in Tumors from BRCA Mutation Carriers
Fong, PC et al., N Engl J Med. 2009 Jul 9;361(2):123-34
Kommentar: Dr. med. Heinz Albrecht/Prof. Dr. med. Markus F. Neurath, Medizinische Klinik 1, Universitätsklinikum Erlangen, 91054 Erlangen, 14.09.09

Kommentar: Dr. med. K. Kast, Universitätsfrauenklinik Dresden, Prof. Dr. R.K. Schmutzler, Stiftungsprofessur “Familiärer Brust- und Eierstockkrebs” Universitätsfrauenklinik Köln

Screening, Surveillance, and Primary Prevention for Colorectal Cancer: A Review of the Recent Literature
Gastroenterology. 2008 35(2):380-99 diskutieren J. Charles et al. die aktuelle Studienlage zur Primär- und Sekundärprävention des kolorektalen Karzinoms (CRC).
Kommentar: Prof. Dr. W. G. Zoller, Katharinenhospital und Zentrum für Innere Medizin, Klinikum Stuttgart, 26.08.09

Einfluss moderner Therapieformen des metastasierten Kolonkazinoms auf die Kostenentwicklung (Cost Implications of New Treatments for Advanced Colorectal Cancer)
Wong et al. Cancer 115, 2081-2091, 2009.
Kommentar: Prof. Dr. Max Reinshagen, Medizinische Klinik I, Städt. Klinikum Braunschweig gGmbH, 22.07.09

Spectroscopic Microvascular Blood Detection From Endoscopically Normal Colonic Mucosa: Biomarker for Neoplasia Risk
Gastroenterology 2008; 135: 1069-1078
Kommentar: Prof. Dr. Stefan Liebe, Abteilung für Gastroenterologie, Universitätsklinik Rostock, 11.06.09

Findings on Optical Colonoscopy After Positive CT Colonography Exam
Am J Gastroenterol 2008; 103: 2068-74
Kommentar: Prof. Dr. J. Mössner, Universitätsklinik Leipzig, 14.06.09

Polyp Size and Advanced Histology in Patients Undergoing Colonoscopy Screening: Implications for CT Colonography
Gastroenterology 2008;135:1100–1105
Kommentar: Prof. Dr. A.H. Hölscher, Prof. Dr. E. Bollschweiler, Klinik für Visceral- und Gefäßchirurgie, Universität Köln, 06.03.09

Family History and Age at Initiation of Colorectal Cancer Screening
J Gastroenterol 2008; 103: 2326-2331
Kommentar: Prof. Dr. K. Beckh, Dr. W. Rimili Medizinische Klinik II Klinikum Worms gGmbH, 25.02.09

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2008

Guidelines for the clinical management of familial adenomatous polyposis (FAP)
Gut 2008; 57: 704-713
Kommentar: Prof. Dr. U.R. Fölsch, Priv.-Doz. Dr. C. Schrader, Kinik für Allgemeine Innere Medizin, Universitätsklinikum Schleswig Holstein, Campus Kiel, 16.09.08

Die Vorsorgekoloskopie rettet Leben – Ergebnisse der Herner Vorsorgedatei
ZGastroenterol 2008; 46:193-200
Kommentar: Prof. Dr. K. Beckh, Dr. W. Rimili, Med. Klinik II, Klinikum Worms gGmbH, 09.06.2008

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2007

Development of Colorectal Tumors in Colonoscopy Surveillance in Lynch Syndrome
Gastroenterology 2007; 133:1093-1098
Kommentar: Prof. Dr. U.R. Fölsch, Dr. C. Sina, I. Med. Klinik, Christian-Albrechts-Universität, Kiel, 12.02.2007

Colonoscopic Screening of First-Degree Relatives of Patients With Large Adenomas: Increased Risk of Colorectal Tumors
Gastroenterology 2007; 133:1086-1092
Kommentar: Prof. Dr. K. Beckh, Dr. W. Rimili, Med. Klinik II, Klinikum Worms gGmbH, 19.11.2007

Factors associated with incomplete colonoscopy: A population based study
Gastroenterology 2007; 132:2297-2303
Kommentar: Prof. Dr. A.H. Hölscher, Prof. Dr. E. Bollschweiler, Klinik für Visceral- und Gefäßchirurgie, Universität Köln, 25.07.2007

Risk of colorectal cancer in juvenile polyposis
Gut 2007; 56:965-967
Kommentar: Prof. Dr. U.R. Fölsch, Dr. S. Ott, Christian-Albrechts-Universität Kiel, 12.07.2007

Clinically Confirmed Type 2 Diabetes Mellitus and Colorectal Cancer Risk: A Population-Based, Retrospective Cohort Study
Am J Gastroenterol 2006; 101:1872-1879
Kommentar: Prof. Dr. K. Beckh, Dr. W. Rimili, Stadtkrankenhaus Worms, 5.7.2007

Type 2 Diabetes Mellitus: The Impact on Colorectal Adenoma Risk in Women
Am J Gastroenterol 2006; 101:1866-1871
Kommentar: Prof. Dr. W. Zoller, Katharinenhospital-Akad. Lehrkrankenhaus der Universität Tübingen, Stuttgart, 24.05.2007

Polyp Miss Rate Determined by Tandem Colonoscopy: A Systematic Review
Am J Gastroenterol 2006; 101:343-350
Kommentar: Prof. Dr. A.H. Hölscher, Klinik und Poliklinik für Visceral- und Gefäßchirurgie, Uniklinik Köln, 26.02.2007

Birth size and colorectal cancer risk: a prospective population based study
Gut 2005; 54:1728-1732
Kommentar: Prof. Dr. K. Beckh, Dr. W. Rimili, Stadtkrankenhaus Worms, 08.03.2007

Impact of endoscopist withdrawal speed on polyp yield: implications for optimal colonoscopy withdrawal time
Pharmacol Ther 2006, 24, 965:971
Kommentar: Prof. Dr. K. Beckh, Dr. W. Rimili, Stadtkrankenhaus Worms, 06.03.2007

Prevention of colorectal cancer by colonoscopic surveillance in individuals with a family history of colorectal cancer: 16 year, prospective, follow-up study
BMJ 2005; 331:1047
Kommentar: Prof. Dr. U. Fölsch, Christian-Albrechts-Universität, Kiel, 02.03.2007

Repeat colonoscopy has a low yield even in symptomatic patients
GI Endoscopy 2006; 64:941
Kommentar: Prof. Dr. J. Mössner, Universitätsklinik Leipzig, 02.03.2007

Impact of colonoscopic Screening Examination for Colorectal Cancer on later Utilization of distal GI Endoscopies
GI Endoscopy 2006
Kommentar: Prof. Dr. W. Hohenberger, Friedrich-Alexander-Universität, Erlangen, 19.01.2007

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2006

Colonoscopic Withdrawal Times and Adenoma Detection during Screening Colonoscopy
NEJ Med Dec, 355:2533-41, R. Barclay et al.
Kommentar: Prof. Dr. W. Zoller, Katharinenshospital, Stuttgart, 19.12.2006

Physical Activity and Survival After Colorectal Cancer Diagnosis
Journal of Clinical Oncology 24, 2006, 3527-3534, J.A. Meyerhardt et al.
Kommentar: Prof. Dr. Beckh, Dr. Rimili, Stadtkrankenhaus Worms, 19.11.2006

Does a negative screening colonoscopy ever need to be repeated?
Gut 2006, 55:1145-1150
Kommentar: Prof. Dr. W. Hohenberger, Chirurg. Klinik der Friedrich-Alexander-Universität, Erlangen, 16.10.2006

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